Lean Gene is a diet pill available exclusively online through Lean-Gene.com.
The supplement works by targeting the UPC2 gene to increase your resting metabolism, helping you lose weight more easily.
Does Lean Gene live up to the hype? Can Lean Gene really interact with your genes to boost weight loss? Keep reading to discover everything you need to know about Lean Gene today in our review.
What is Lean Gene?
Lean Gene is a weight loss supplement that comes in the form of a capsule.
As the name suggests, Lean Gene targets the genes within your body to accelerate weight loss results.
According to Janet Hadvill, the nutritionist and researcher who created the formula, Lean Gene targets the UPC2 gene and increases your resting metabolism to activate fat burning.
In fact, Lean Gene is purportedly the first nutritional supplement to target this “fat burning gene.” While other supplements boost metabolism using stimulants, herbs, and plants, Lean Gene uses unique ingredients to interact with your body’s genetic data, changing the way your body burns fat.
How Does Lean Gene Work?
Lean Gene uses a blend of ingredients to target a fat burning gene called UPC2.
The formula contains a blend of yerba mate, betaine, choline, green tea extract, cinnamon, and resveratrol. Together, these natural ingredients purportedly target your UPC2 gene, boosting your metabolism and helping you burn more fat than you normally would.
Your metabolism is crucial for weight loss. It controls how much energy your body burns at rest, and it dictates how your body transforms calories into energy.
People with a fast metabolism burn 5x more fat than people with a slow metabolism, according to some studies. That means people with a fast metabolism have a fat burning furnace within themselves. That fat burning furnace helps complement a diet and exercise routine, making it easier to lose weight.
How the UPC2 Gene Works
Lean Gene is the only fat burning supplement designed to target a “fat burning gene” called UPC2.
Here’s how the makers of Lean Gene explain how the formula interacts with your genetic data:
“Lean Gene targets the UPC2 gene and increases your resting metabolism.”
UPC2 is called the fat burning gene because it’s responsible for creating a protein linked to metabolism and fat burning:
“UPC2 is the gene that triggers the creation of a protein that turns on resting metabolism and activates fat burning…The more UPC2 you have, the more fat your body will burn at rest.”
By that logic, Lean Gene purportedly raises levels of the UPC2 gene within your body. The company flips genetic science on its head by claiming to raise levels of genes within your body, making it easier to burn significant fat without much effort.
Here’s the three step process Lean Gene uses to help you lose weight:
- Step 1) It targets the UPC2 gene pathway in your body, increasing fat burning.
- Step 2) It increases your resting metabolism, helping your body naturally burn more calories at rest. Instead of storing the calories you eat as fat, your body spends those calories as energy.
- Step 3) Helps resist fat formation, allowing you to continue to eat fatty, unhealthy, junk food while still losing significant amounts of weight with Lean Gene.
In fact, the makers of Lean Gene claim you’ll see positive results within the first 72 hours of taking the formula, and most people experience a “total body transformation” within 30 to 180 days.
Janet, the nutritionist who created the formula, even claims to have lost 15lbs in her first 21 days of taking Lean Gene.
What Does Lean Gene Do?
Lean Gene exhibits all of the following benefits, according to the official website:
- Increase fat burning by 543%
- Decrease cravings and hunger
- Support healthy blood sugar
- Target your master fat burning gene, UPC2
- Burn stubborn belly fat
- Burn fat without vigorous exercise
The Story Behind Lean Gene
Lean Gene was created by a woman named Janet Hadvill, a certified nutritionist. Janet calls herself the “Gene Girl” because she has studied epigenetics, gene therapy, and genomics while working as a nutritionist for the past 18 years.
Janet has a twin sister who never struggled with weight. Her sister ate anything she wanted, rarely exercised, and never gained a pound.
Janet, on the other hand, was the opposite. She gained significant weight over the years and struggled to lose it with diet and exercise.
That’s when Janet stumbled on a scientific breakthrough on a research trip in Brazil.
In a remote village, Janet discovered a “Brazilian water recipe” that reactivates your UPC2 gene, increases your resting metabolism, and makes it easy to lose weight.
After losing significant weight with the Brazilian water recipe, Janet wanted to share the formula with the world, so she launched Lean Gene.
Lean Gene Ingredients
Lean Gene contains a collection of plants, herbs, and other ingredients to help you lose weight by increasing genetic activity within your body. It sounds weird, but here’s how each ingredient in the Lean Gene works, according to certified nutritionist Janet Hadvill:
Yerba Mate: Lean Gene contains yerba mate, a plant native to South America used for centuries in traditional medicine. Janet claims the yerba mate in Lean Gene targets the UPC2 gene and modulates the expression of the gene, increasing your metabolic rate and helping you burn more calories. Janet even claims the ingredient works without dieting or exercising, making it easy to effortlessly lose weight. Janet also claims yerba mate increases energy, boosts mental focus, enhances physical performance, protects against infections, and boosts your immunity system, among other benefits.
Betaine: Lean Gene contains betaine, a lipotrope that enhances metabolism and helps break down fat within the body. According to Janet, the betaine in Lean Gene helps regulate blood sugar and insulin resistance while shutting down the genes responsible for belly fat formation.
Choline: Choline is a lipotrope found in all mammals. Typically found in nootropic supplements for its effects on brain health, choline can purportedly help redistribute body fat and boost cognition when used in conjunction with inositol. Many people get their recommended daily consumption of choline from eggs.
Inositol: Inositol can purportedly control appetite and cravings while relieving depression in Lean Gene, according to Janet. It works in conjunction with inositol to help redistribute body fat while interacting with brain chemicals.
Cinnamon Bark Extract: Commonly found in diabetes supplements and blood sugar support formulas, cinnamon bark extract helps support healthy glucose metabolism and insulin levels. Today, researchers know cinnamon bark supports blood sugar by regulating the enzyme responsible for metabolism, making it easier to control cravings, manage fat, and increase fat breakdown, among other benefits.
Polyphenols: Lean Gene contains polyphenols from two natural ingredients, including grape seed extract and green tea. Grape seed extract is rich with polyphenols like resveratrol that support inflammation throughout your body, while green tea extract is rich with polyphenols like EGCG linked to fat burning. According to Janet, both of these ingredients stimulate fat breakdown, control appetite, and even impact the expression of fat storing genes to reduce body fat.
Resveratrol: Lean Gene contains resveratrol from two sources, including grape seed extract and a separate, individual source of powdered resveratrol. Studies show resveratrol has antioxidant effects, helping with belly fat and blood sugar.
Chromium: Janet describes chromium as a “powerful plant extract” that supports your fat burning genes. Chromium is not a plant extract: it’s an essential mineral. Studies show diabetics and people with blood sugar control issues often have low levels of chromium, and that chromium supplementation may be able to help.
Butyrate: Lean Gene contains an ingredient called “butyrate.” It’s a four-carbon short-chain fatty acid produced when your gut ferments dietary fibers. As your gut breaks down fiber, it releases butyrate. According to Janet, the butyrate in Lean Gene supports healthy gut bacteria while also increasing metabolism and fat burning. It’s true that butyrate can support healthy gut bacteria by acting as a prebiotic: your gut bacteria need fuel to survive and thrive, and dietary fiber provides them with a source of prebiotics.
Overall, the ingredients in Lean Gene interact with your genes, metabolism, and blood sugar in various ways, making it easy to effortlessly lose weight.
In fact, thanks to the ingredients in Lean Gene, “you literally can’t fail” to lose weight while taking Lean Gene, according to Janet.
How Much Weight Can You Lose with Lean Gene?
According to the makers of Lean Gene, most people “see positive results within the first 72 hours” of taking Lean Gene.
People have purportedly lost “71 pounds of fat in just weeks” by taking the Lean Gene formula.
The longer you take Lean Gene, the better the results will be. People who take it for 30 to 180 days, for example, can lose significant weight.
Janet claims to have lost 15lbs in 21 days just by taking two capsules of Lean Gene per day. She claims she “started dropping fat like crazy” after taking Lean Gene.
Janet also claims that as long as your “lean gene” stays activated, you can eat whatever foods you like as much as you like, including bread, pizza, burgers, and ice cream; your gene continues to burn fat effortlessly regardless of what you eat or how much you exercise.
Scientific Evidence for Lean Gene
Janet Hadvill, the creator of Lean Gene, makes many significant claims on the official website. She claims to have created a formula that interacts with your genetic data, for example, to help you lose weight with minimal dieting and exercising.
Is any of this information backed by science? Can you really lose weight by targeting a special gene? We’ll review some of the science below.
First, Janet claims to have conducted multiple real world tests on Lean Gene. During her research trip to a village in Brazil called Cândido Godói, for example, Janet discovered “each local resident” had their UPC2 gene, the “lean gene,” switched on. Genetic testing is expensive, yet Janet claims to have tested residents in a remote village in Brazil, giving her instant information about which genes were turned on and turned off.
Cândido Godói is a village of 6,000 people in Rio Grande do Sul, Brazil. The village is famous for having unusually high rates of twins. Because of this phenomenon, the village has attracted significant attention from the genetics community – including from genetic researcher Janet Hadvill.
After visiting the village, Janet claims to have tested the genetics of a group of overweight American volunteers. Here’s how that trial worked:
Janet gathered a group of friends, family members, and coworkers ranging between 40 and 85 years of age; some members of the group were slim, while others were obese
All overweight American volunteers had their UPC2 gene “switched off”
Janet’s twin sister, who had never struggled with weight loss despite being genetically identical to Janet, had the UPC2 gene switched on
After the test, Janet personally used Lean Gene to lose 15lbs in 21 days, ultimately losing 71lbs by taking the formula.
After testing the genetics of her volunteers, Janet told them to take Lean Gene. Then, all members of the group increased energy and looked and felt younger – all without making drastic changes to their diet or lifestyle.
Janet did not publish her study in a peer-reviewed medical journal. However, she cites dozens of studies on the Lean Gene website proving various claims.
In this study, for example, researchers found a connection between resveratrol and weight loss. Researchers analyzed dozens of trials involving hundreds of patients, concluding that resveratrol intake significantly reduced weight, body mass index, and waist circumference, among other benefits.
Janet also cites this study on green tea extract linking it to weight loss. Researchers found a correlation between green tea extract and weight loss, with participants losing 0.2 to 3.5kg more weight than a placebo with green tea extract.
There is a gene called UPC2 that may be linked to metabolism. In this study, for example, researchers found deletion of the UPC2 gene modified homeostasis, altering your body’s metabolism. However, it’s unclear how the ingredients in Lean Gene “turn on” the gene, alter the gene’s activity, or increase levels of the gene within your body.
Overall, Lean Gene contains a blend of proven weight loss ingredients like green tea extract and resveratrol. These ingredients have been shown to boost metabolism and make it easier to lose weight. However, there’s no evidence Lean Gene interacts with your genetic data, alters gene activity, or changes your body at a genetic level to help you lose weight.
Lean Gene Ingredients Label
The makers of Lean Gene disclose the full list of ingredients and dosages in the formula upfront, including the breakdown of each individual ingredient and its concentration. It’s a higher level of transparency than we typically get with weight loss drugs.
Here are the ingredients in each two capsule serving of Lean Gene, according to the official website:
- 250mg of yerba mate
- 200mg of TMG (betaine anhydrous)
- 100mg of magnesium beta hydroxybutyrate
- 100mg of calcium beta hydroxybutyrate
- 100mg of grape seed extract with 85% polyphenols
- 100mg of green tea leaf extract with 95% polyphenols and 50% EGCG
- 100mg of organic Ceylon cinnamon bark
- 50mg of trans resveratrol with 98% trans-resveratrol
- 50mg of sodium beta hydroxybutyrate
- 20mg of inositol
- 80mg of choline (15% DV)
- 15mg of calcium (1% DV)
- 10mg of magnesium (2% DV)
- 100mcg of chromium (286% DV)
- Other (inactive) ingredients, including gelatin (to create the capsule), magnesium stearate, microcrystalline cellulose, and silicon dioxide (as fillers, binders, and preservatives).
Lean Gene Pricing
Lean Gene is priced at $59 per bottle, although the price drops as low as $44 or $49 per bottle when ordering multiple units.
Here’s how pricing breaks down:
- 1 Bottle: $59 + Free Shipping
- 3 Bottles: $147 + Free Shipping
- 6 Bottles: $264 + Free Shipping
Each bottle contains 60 capsules (30 servings), giving you a 30 day supply of weight loss pills.
Bonuses Included with Lean Gene
If you buy Lean Gene today, you get three bonus products to help you lose weight and maximize the effects of the formula, including:
Free Bonus #1: 7-Day Perfect Body Blueprint: This eBook teaches you how to lose fat in a week by releasing trapped fat and retaining water overnight. If you want to look slimmer as quickly as possible, then this guide can help.
Free Bonus #2: 24-Hour, Stop Your Fat Storage Gene Plan: Janet Hadvill, the creator of Lean Gene, is a big believer in using genes to optimize fat burning. In this guide, you can discover how to lose your belly fat, boost energy, and support cardiovascular health by using natural foods and lifestyle habits to alter your genetic activity.
Free Bonus #3: Stop Fat Storage Tonic & Smoothie Recipes: The right tonics and smoothies can optimize your body’s fat burning. This eBook contains several quick, delicious, and nutritious recipes to increase fat burning.
Lean Gene Refund Policy
If you don’t lose significant weight within 60 das of taking Lean Gene, or if you’re unhappy with the supplement for any reason, then you can request a complete refund with no questions asked.
Who is Janet Hadvill?
Janet Hadvill claims to be a certified nutritionist with 18 years of experience in a clinical setting.
Clinical nutritionists are different from registered dietitians (RDs). Registered dietitians must meet strict requirements to practice as RDs, including proving their credentials via the Commission on Dietetic Registration.
Clinical nutritionists, meanwhile, have different educations and backgrounds. Some are authorized via the American Association of Nutritional Consultants to be a Certified Nutrition Specialist. However, Janet does not claim to be a Certified Nutrition Specialist. She simply claims to be a “certified nutritionist.”
Janet also claims to have 18 years of experience studying epigenetics, gene therapy, and genomics.
Despite her extensive experience, Janet makes unusual errors during the Lean Gene presentation.
She describes chromium, an essential mineral, as a “powerful plant extract,” for example. She also claims to have developed a “100% plant based” formula made from “100% pure plant extracts”, yet she uses animal-based ingredients like gelatin.
Janet also claims to have lost 71lbs by taking Lean Gene, including 15lbs within her first 21 days of taking the supplement.
As far as we can tell, Janet Hadvill is not a real person: it’s a pseudonym invented by All Natural Nutrition to sell weight loss programs online.
About All Natural Nutrition
Lean Gene is a weight loss formula from All Natural Nutrition, a Chicago-area supplement company.
There’s limited information online about All Natural Nutrition, how Janet Hadvill is connected with the company, or what types of products the company sells. The All Natural Nutrition website, all-naturalnutrition.com, redirects to a supplement called HSD Activate that claims to help you lose weight with no dieting or exercise.
Nevertheless, All Natural Nutrition claims to bottle its supplements in the United States and make its supplements in a GMP-certified, FDA-registered facility.
You can contact the makers of Lean Gene via the following:
- Email: email@example.com
- Mailing Address: 1301 Ridgeview Dr, McHenry, IL 60050, USA
Lean Gene is a unique weight loss formula created by All Natural Nutrition and Janet Hadvill.
By taking two capsules of Lean Gene daily, you can purportedly boost the activity of a gene called UPC2, helping you lose 15lbs in 21 days without dieting or exercising.
To learn more about Lean Gene and how it works or to buy the nutritional supplement today, visit the official website at Lean-Gene.com >>>
- Weight Loss Tips That Work: Easy Tips to Lose Weight Fast in 2022
- Exipure Reviews: What are Customers Saying? Critical Announcement!
- Top 22 Best Weight Loss Pills in 2022
- Best Weight Loss Gummies (2022)
The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team. Please know we only recommend high-quality products.
Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.