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ExaFlex Reviews: Joint Supplement Ingredients That Work or Not?

ExaFlex is a nutritional supplement made by Camas, a Washington-based company named Nutriomo Labs.

By taking three capsules of ExaFlex daily, you can purportedly stop joint pain by taking advantage of a “10-second Swedish solution.” The supplement contains a mysterious ingredient called “the comfort compound” that may work more effectively than morphine and other prescription pain medication, according to ExaFlex reviews on the official website.

Does ExaFlex stop joint pain? How does ExaFlex work? Please keep reading to discover everything you need to know about this joint pain supplement and how it works.

What is ExaFlex?

ExaFlex is a joint pain supplement sold exclusively online through Priced at $49 per bottle, the supplement claims to stop all types of joint pain quickly using natural ingredients.

According to the makers of ExaFlex, joint pain is linked to low levels of a compound in your brain. ExaFlex targets your brain to restore this compound, rapidly relieving pain. The company also cites a study claiming their formula “is more powerful than morphine” despite being made from natural ingredients.

Here’s how the manufacturer describes the effects of ExaFlex:

“A group of scientists in Sweden was stunned recently when they…discovered blood samples that showed a certain brain compound is 50% lower in people who are in pain….Now you can restore your levels of this brain compound to normal pain-free levels quickly and easily.”

Just take three capsules of ExaFlex daily to raise levels of this compound in your brain, rapidly stopping pain.

How Does ExaFlex Work?

ExaFlex works using a blend of 8 pain-killing ingredients. Like other joint pain relief supplements, ExaFlex contains a blend of herbs, plants, vitamins, and minerals linked to joint pain relief.

According to the ExaFlex website, one ingredient in the formula was chosen because it “reduces inflammation, and increases pain tolerance” while being a natural ingredient. Typically, doctors recommend taking a non-steroidal anti-inflammatory drug (NSAID) to reduce inflammation.

Endorphins are crucial for pain relief. In fact, according to the creators of ExaFlex, endorphins “are pain’s kryptonite” and “pain doesn’t stand a chance against endorphins.” Higher endorphin levels are associated with reduced pain perception and a higher threshold. Another ingredient in ExaFlex raises endorphin levels within days, helping it provide similar effects to powerful pain medication.

When your body has low endorphin levels, it makes you more sensitive to pain. ExaFlex works by raising endorphin levels, increasing your pain tolerance.

Low endorphin levels also create a negative feedback loop:

  • When your endorphin levels are low, you’re more susceptible to joint pain and overall body pain
  • When you have joint pain, you don’t want to walk, exercise, or work out because it hurts too much
  • When you don’t exercise, your body keeps endorphin levels low, leading to more pain

It’s a devastating cycle that ExaFlex claims to stop. Together, the ingredients in ExaFlex raise endorphins and provide other benefits, helping you tackle pain in multiple ways.

Who Created ExaFlex?

The creator of ExaFlex, Frank Wallings, used to suffer from extreme pain. He had a “broken back” and was virtually immobile – until he discovered the 10-second joint pain solution from Sweden and added it to the ExaFlex formula:

“…I’d tried all those pills and creams that promised me pain relief but didn’t work. But this natural discovery very quickly wipes out years of nagging aches and even the worst bone-on-bone chronic pains.”

Frank claims he spent over $16,500 on healthcare costs to cure his back pain. He was gobbling pain pills “like candy” and getting cortisone injections, acupuncture, and other unique treatments – all while still suffering extreme pain. Doctors and hospitals were getting rich off of him.

Frank eventually talked to his nephew Nathan about his back pain. Nathan is not a doctor, but he is in medical school, and he used his medical expertise and experience to help formulate ExaFlex. Nathan is an “insider” who knows how the pharmaceutical and medical industries work.

To make a long story short, Nathan and Frank started researching natural cures for back pain. Eventually, they stumbled upon a back pain treatment from Sweden.

Frank and Nathan tested the formula and verified it worked. Today, thanks to Frank’s pain relief journey and Nathan’s medical expertise, the pair have released a supplement that has helped over 12,000 people rapidly relieve back pain.

ExaFlex Ingredients

Any joint pain relief supplement can claim to cure joint pain overnight. However, only the best joint pain supplements have the ingredients to back up that claim.

Here are all of the ingredients in ExaFlex and how they work, according to Frank, Nathan, and the team behind ExaFlex:

The Comfort Compound (MSM): The makers of ExaFlex make quite a deal about MSM, which they describe as “the comfort compound.” The pain relief medication industry tries to hide this cure from the world to protect their pain pill profits. According to Frank, Nathan, and the ExaFlex team, the comfort compound is a natural compound absorbed by the root systems of plants as part of the planet’s natural sulfur cycle. Multiple studies show this ingredient can help support joint pain relief in numerous ways.

Methionine: ExaFlex contains methionine, a natural amino acid. Amino acids are the building blocks of proteins, and they play a crucial role throughout your body. Methionine is essential for building and maintaining muscles, bones, and soft tissue. Frank and Nathan describe methionine as a “little-known natural pain-relieving powerhouse” that was traditionally used to treat pancreatitis but is now used in joint pain relief. In studies ranging from 10 weeks to 12 months, researchers found that methionine produced critical pain-reducing neurochemicals and hormones, making it a practical way to stop the pain.

Scientific Evidence for ExaFlex

ExaFlex has not completed clinical trials, nor has the FDA approved using ExaFlex for treating joint pain. However, the supplement contains FDA-approved ingredients, and these ingredients have completed clinical trials from independent third parties verifying they provide some amount of pain relief.

The only listed ingredient in ExaFlex is methionine. Also known as L-methionine, it’s a popular nutritional supplement ingredient found in many other joint pain relief formulas. The supplement contains 25mg of methionine.

In this 2012 study, researchers evaluated the effects of methionine and glucosamine on rats with arthritis. Researchers found that rats experienced a significant improvement in arthritis symptoms after taking methionine. The result was slight but noticeable. Researchers believe methionine works by suppressing specific biomarkers linked to inflammation and pain. Rats took a dose of 200mg/kg of methionine per day, which is hundreds of times higher than the dose used in ExaFlex.

However, other studies have found that diets rich in methionine can increase the severity of arthritis symptoms. Research shows that a high-methionine diet modulates IGF-1 related gene expression linked to joint pain.

The makers of ExaFlex make a big deal out of an ingredient called methylsulfonylmethane (MSM). MSM is one of the world’s most popular joint pain supplement ingredients, and many joint pain sufferers take MSM daily to help relieve joint pain. In this 2006 study, researchers found that taking MSM helped with osteoarthritis pain in the knee. Participants took 3g of MSM daily and experienced significant improvements in pain and physical function.

The most prominent ingredient in ExaFlex is glucosamine sulfate. It’s a popular joint pain relief supplement ingredient. In this 2012 study published in Arthritis Research & Therapy, researchers analyzed the effects of glucosamine sulfate on osteoarthritis in humans. Researchers found that glucosamine appeared to offer anti-inflammatory effects when used at high concentrations. However, researchers cautioned that the current treatment doses of glucosamine sulfate (1,500mg per day) were insufficient for raising levels significantly in plasma and tissue.

ALSO READ:Joint N-11 Reviews

The study found that glucosamine sulfate led to a considerable reduction in the need for non-steroidal anti-inflammatory drugs and other pain medication. Other studies have found that a daily dose of around 1,500mg of glucosamine sulfate per day is sufficient for enjoying significant long-term joint pain relief. Because of these results, glucosamine sulfate remains one of the most popular joint pain relief supplement ingredients available today.

The manufacturer of ExaFlex discloses all ingredients and dosages upfront, making it easy to see exactly what’s inside ExaFlex and how the supplement compares to other popular supplements sold online today. Most of the formula (1,500mg out of 2,100mg total) consists of glucosamine sulfate, with smaller doses of Boswellia serrata extract (200mg), chondroitin sulfate, and turmeric (150mg each), and quercetin, methionine, MSM, and bromelain (25mg each).

Overall, ExaFlex could work similarly to other joint pain relief supplements sold online today because it appears to contain methionine, MSM, and other proven joint pain relief ingredients. However, with dosage appearing to be much lower than competing joint pain supplements at this price range, it’s difficult to confirm that ExaFlex will cure back pain overnight, eradicate decades of joint pain, or solve serious medical conditions related to joint pain – like arthritis or osteoarthritis.

ExaFlex Ingredients Label

The makers of ExaFlex disclose all ingredients and dosages on the label. There are no proprietary formulas, and the company transparently discloses ingredients and dosages upfront.

Every three capsules serving of ExaFlex contains the following ingredients and dosages:

  • 1,500mg of glucosamine sulfate
  • 200mg of Boswellia
  • 150mg of chondroitin sulfate
  • 150mg of turmeric
  • 25mg of quercetin
  • 25mg of methionine
  • 25mg of methylsulfonylmethane (MSM)
  • 25mg of bromelain

Other (inactive) ingredients, including cellulose (to create the vegetable capsule) and rice flour

ExaFlex Ingredients Label IMAGE

ExaFlex Reviews: What Do Customers Have to Say About ExaFlex?

The official ExaFlex website is filled with positive reviews from happy customers. Some customers claim to have dealt with serious pain for decades before finding relief with ExaFlex. Others claim ExaFlex worked better for them than morphine, fentanyl, and other high-powered pain relievers.

Here are some of the stories shared on the ExaFlex website:

One woman claims she had terrible knee pain after a car accident but got rid of it “within just days” by taking ExaFlex. That customer describes the formula as “a pain relief Godsend.” Although she was skeptical at first, that woman later praised ExaFlex for being straightforward and effective.

Another user claims he had awful back pain and arthritis in his joints. He was worried he would suffer pain in these areas for the rest of his life. The pain was so severe that he was “close to needing a wheelchair and getting ready to be thrown into a nursing home.” After taking ExaFlex, however, that man claims his pain rapidly disappeared, and he’s now “Happy and mobile again” with “a second lease on life.”

Multiple customers claim to have stopped taking over-the-counter pain medication after taking ExaFlex. One customer claims he no longer takes Aleve, Advil, Tylenol, or pain relief patches “because this [ExaFlex] relieves my pain ten times better.”

Frank, the person who helped create ExaFlex to cure his joint pain, claims he noticed significant improvements after just three days of taking the supplement. He got out of bed more easily, had more energy, and had significantly less joint pain, among other benefits. Despite dealing with debilitating joint pain for years, Frank claims his stiffness and pain were “about 50% less than normal” after just three days of taking ExaFlex.

Another customer claims she went to an orthopedic specialist and got steroid shots for $2000 apiece to treat her joint pain. Within a week of taking ExaFlex, that woman had noticeable pain relief. Today, she claims to have achieved around 30% pain relief with ExaFlex.

Another reviewer claims her “pain is gone” after taking ExaFlex for a month and that she has seen a definitive improvement in her pain and stiffness. That woman’s pain and stiffness were so bad that she could barely move her wrists and hands. Since taking ExaFlex, however, that woman’s pain is virtually disappeared.

Overall, customers seem to agree that ExaFlex works as advertised to stop pain using natural ingredients rapidly, and multiple customers claim the formula is more potent than over-the-counter pain medication, prescription pain medication, and other high-powered solutions.

ExaFlex Pricing

ExaFlex is priced at $49 per bottle, although the price drops as low as $39 or $33 per bottle when ordering multiple units.

Here’s how pricing breaks down when ordering ExaFlex online through

  • One Bottle ExaFlex: $49.00 Each / Free Shipping
  • Three Bottles ExaFlex: $117.00 Total / Free Shipping
  • Six Bottles ExaFlex: $198.00 Total / Free Shipping

All prices include free shipping to the United States. Each bottle includes a 30 day supply of ExaFlex or 60 capsules.

ExaFlex Pricing IMAGE

ExaFlex Refund Policy

ExaFlex comes with a 365-day moneyback guarantee.

If you’re unhappy with ExaFlex or how it works, or if you did not rapidly relieve joint pain using ExaFlex, then you are entitled to a complete refund with no questions asked. Contact the company and return your bottle (or bottles) of ExaFlex to initiate the refund process.

About Nutriomo Labs

ExaFlex is made by a supplement company named Nutriomo Labs Pte Ltd. That company is based in Camas, Washington.

Nutriomo Labs partnered with a man named Frank Wallings to create ExaFlex. Frank teamed up with his nephew, a man in medical school named Nathan, to create ExaFlex, which means ExaFlex was formulated with some medical expertise.

You can contact Nutriomo Labs and the ExaFlex team via the following:

  • Email Form:
  • Mailing Address: 3242 NE 3rd Avenue #1043, Camas, WA 98607

Final Word

ExaFlex is a nutritional supplement company that claims to relieve joint pain using natural ingredients rapidly.

Featuring “the comfort compound,” methionine, and six other pain-relieving ingredients, ExaFlex can purportedly restore flexibility, relieve years of arthritis pain, and relieve pain more effectively than over-the-counter pain medication, according to the official website.

To learn more about ExaFlex or buy the joint pain relief supplement today, visit the official website at

RELATED:Best Joint Supplements

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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