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Best Medicinal Mushroom Supplements to Buy (Top Products List)

Medicinal mushrooms are becoming more popular with each passing day as researchers continue to unravel new psilocybin benefits. These benefits are drawing more consumers to mushroom-related products. Currently, it’s even easier to buy medicinal mushrooms and mushroom supplements online.

Psilocybin is a controlled substance, which is why it’s not available in most mushroom supplements. However, mushroom supplements deliver other types of mushrooms with proven nutritional or health benefits. With many mushroom supplement companies engaged in making mushroom supplements, consumers find it challenging to choose the best products.

To help consumers get the best mushroom supplements, we separated the best medicinal mushroom supplements from the rest of the products on the market. Keep reading this review to discover the top 29 mushroom supplements to buy in 2021.

The Best Medicinal Mushroom Supplements in 2021

Our editorial team consulted mushroom supplement companies and analyzed lab reports to develop this list of the best mushroom supplements 2021. It also compared top mushroom supplements available on the market today. After extensive discussion, here’s the list of the best 29 mushroom formulas of 2021:

Onnit Shroom Tech SPORT: One of the best mushroom supplements for daily use
Four Sigmatic:This most popular medicinal mushroom brand combine proven organic mushrooms in its products
Real Mushrooms:A comprehensive collection of mushroom formulas for immune and brain health
MUD\WTR: best mushroom supplement drink blend for protecting your youthfulness
Mushroom Defense: Mushroom Defense contains substantial doses of medicinal mushroom extracts
Organixx 7M+ :These fermented mushroom pills are rich in antioxidants
Pure Essence MyPure Lion’s Mane: A mushroom supplement that supports brain health and immunity
Genius Mushrooms: A broad range of mushroom supplements are available from Genius Mushrooms
Mushroom Revival: Mushroom revival offers mushroom supplements that promote a five-second wellness routine
Earth Nutri Performance Energy + Focus: This nootropic and mushroom formula improves mental and physical performance throughout the day
FreshCap: Energy and endurance-boosting mushroom capsules
VidaCap: VitaCap offers powdered and capsule mushroom supplements that promote vitality and energy
Shroomy: The first mushroom gummi product in the world
Ceremony Mushrooms: Through its mushroom supplements, the company promotes health and wellness in four different ways
Gundry MD Mushroom Vitality: This mushroom supplement combines the most powerful medicinal mushrooms in the world
Circadian Wellness: Featuring high-end mushroom supplements, this company specializes in functional mushrooms
VitaPost Immune Support: A wide range of nutritional ingredients are present in this mushroom supplement for optimal immunity
MycoPhyto Complex: A potent mushroom blend of high-quality medicinal mushrooms
Brain Forza Organic Lion’s Mane Mushroom: This organic Lion’s Mane Mushroom formula will boost your mental and immune health
Goldmine Supershroom Powder: The formula contains four top medicinal mushrooms to boost the immune system Magic Mushroom: Relax and stay calm with this delicious chocolate formula of mushroom extracts
Spore: Adaptogens in Spore help your immune system function properly
Vital Plan Adaptogen Recovery: A herbal formula to strengthen immunity and general well-being
The Drug Store Adaptogenic Mushrooms: A range of top-class medicinal mushroom supplements for brain and immunity wellness
Botany Cordyceps Millitaris Extract: Third-party lab testing confirms the quality of this Caterpillar Fungus powder
Plant People WonderDay: You can boost your immunity and brain health with these adaptogens formulated by doctors
5 Mushrooms Reserve Blend: This mushroom supplement comes in an attractive bottle that includes the five most popular medicinal mushroom extracts
MindHoney: An excellent daily cognitive supplement
Vital Plan Brain Boost: Physician formulated natural nootropic blend

To learn more about these top-ranked mushroom supplements, here’s a rundown of each product or brand:

Onnit Shroom Tech SPORT

Supplement Classification
Active Components: Each Shroom Tech SPORT formula capsule delivers 1.2g of cordyceps and 930mg of an adaptogen mix consisting of green tea leaf extract, ashwagandha, Rhodiola, and astragalus leaf extract. This makes it one of the more powerful medicinal mushrooms listed here
Quantity Per Pack: 28/84 Capsules
How To Serve It? Recommended to take four capsules daily
Guarantee: 90-day money-back guarantee
Price: Shroom Tech SPORT supplement currently costs $25 per package

Onnit is a household name when it comes to the best medicinal mushroom supplements. The supplement company backed by Joe Rogan markets Shroom Tech SPORT as a daily energy mushroom formula. According to the manufacturer, users should take one formula capsule daily to support daily energy in several ways.

On this list, Onnit Shroom Tech SPORT takes the first slot mainly because it’s one of the few mushroom formulas listed here that are backed by a clinical trial. The company invested in clinical trials for its supplements, including the Shroom Tech SPORT formula.

According to one trial, the supplement increased workout performances like bench press reps, bench press and back squat reps, and cardio performance by significant margins. Shroom Tech SPORT delivers plant-based ingredients, vitamin B12, and a mushroom complex to promote energy in several ways.

Four Sigmatic

Supplement Classification
Active Components: Currently, the company runs a lineup of the best mushroom supplements, including ground mushroom coffees, Blend Mix, and plant-based protein powders in several flavors
Quantity Per Pack: 30 servings in each pack
How To Serve It? Take two scoops daily
Guarantee: 100% money-back guarantee
Price: The products are currently priced from $20 upwards

Four Sigmatic is among the best mushroom supplements to consider buying in 2021. The formula has appeared on several media outlets like TIME, Women’s Health, and Goop for coffees and vegan proteins. The company combines the benefits of other plant-based ingredients with mushroom extracts to make highly effective mushroom supplements.

The mushroom supplements from Four Sigmatic fall into three main categories:

  • Think—for focused mornings and afternoons
  • Defend—for daily nutrition, immune and gut support
  • Chill—for relaxation at any time

Users can also buy the products by prototype, selecting from coffees, proteins, and Caicos, among other options. Importantly, Four Sigmatic is a Finland-based company that has used Chaga and lion’s mane for hundreds of years.

Importantly, all mushroom supplements from this company are USDA Organic certified, making Four Sigmatic one of the best medicinal mushroom manufacturers and mushroom formula providers available today.

Real Mushrooms

Supplement Classification
Active Components: These medicinal mushroom powders contain ingredients such as Chaga mushroom and reishi mushroom extracts. Both Chaga and reishi mushrooms are effective to boost your overall immunity
Quantity Per Pack: Powdered formulas contains 45g to 60g mushroom extract
How To Serve It? Half to one teaspoon per serving
Guarantee: N/A
Price: Most mushroom powders and capsules from Real Mushrooms cost between $25 and $35, making it one of the best-value providers

This family-owned mushroom farm boasts forty years of mushroom growing experience. Real Mushrooms delivers more real-world expertise than several mushroom supplement companies listed here combined. Currently, the company focuses on capsules and powders.

Users can choose specific mushroom pills and powders such as Chaga, tremella, reishi, turkey tail, and cordyceps mushroom products. Alternatively, users can choose a mushroom mix of several mushroom extracts like ‘5 Defenders’ or ‘Mushroom Hot Chocolate Mix,’ among other products.

The company is based in a small coastal town in northern Vancouver, producing affordable yet high-quality and best medicinal mushroom supplements.


Supplement Classification
Active Components: Each supplement serving provides cacao, turmeric, chia, sea salt, and cinnamon combined with four mushroom ingredients—Chaga, lion’s mane, cordyceps, and reishi mushroom extracts
Quantity Per Pack: 30 servings
How To Serve It? Take 6g per serving
Guarantee: N/A
Price: The product is currently priced at $40, including shipping charges

This mushroom supplement is a coffee alternative that utilizes organic ingredients to deliver specific benefits. MUD\WTR works to give users the energy-boosting benefits of coffee without exhausting their bodies with caffeine.

The formula contains no other ingredients than the mentioned ones. It’s ideal for those who want to give their bodies a boost of energy to start the day without the unpleasant side effects of caffeine. Each serving of MUD\WTR delivers one-seventh of caffeine available in coffee.

Using USDA Organic certified ingredients, a Ritual Starter Kit of MUD\WTR comes with a free frother and 30 servings of mud.

Mushroom Defense

Supplement Classification
Active Components: Mushroom Defense has a mushroom blend of turkey tail, lion’s mane, cordyceps, and shiitake mushroom
Quantity Per Pack: 60 pills
How To Serve It? Take two pills every day with a meal
Guarantee: The manufacturer offers a 67-day moneyback guarantee for every supplement order, just if it doesn’t serve the users’ needs
Price: $60

Mushroom Defense is designed to fight fatigue and protect against cognitive decline. It also delivers other protective benefits. As stated by the manufacturer, Mushroom Defense gives users a clean and energized dose of protection against bacterial and viral threats while leaving them feeling energized.

The formula also helps improve memory and focus, among other benefits unavailable from other mushroom supplements.

Each serving of the supplement delivers ten functional mushrooms that work to support the benefits in multiple ways. Mushroom Defense is one of the most popular mushroom supplements on the market.

Organixx 7M+

Supplement Classification
Active Components: Chaga and Turkey tail mushrooms, Shiitake, reishi mushroom extract, cordyceps, maitake, and Lion’s Mane organic mushrooms
Quantity Per Pack: 60 veggie caps
How To Serve It? Take two fermented mushroom pills daily
Guarantee: 365-day money-back guarantee
Price: Organixx’s current price is $55

The 7M+ mushroom supplement from Organixx is designed to support the immune system. This fermented mushroom formula contains a blend of seven powerful mushrooms with pre-immune support and anti-aging properties. The organic mushrooms used to make this formula are turkey tail, Shiitake, maitake, Chaga, lion’s mane, cordyceps, and cordyceps.

Each of the medicinal mushrooms has been fermented to deliver maximum nutrition and bioavailability. The manufacturer has also included a unique ingredient missing in other mushroom supplements listed here—kelp extract. This remarkable component in the 7M+ formula claims to support healthy liver function.

According to the manufacturer, users should take 7M+ daily to supply the body with mushroom extracts and beta-glucans. It also delivers antioxidants and other plant-based compounds to support multiple benefits.

Pure Essence MyPure Lion’s Mane

Supplement Classification
Active Components: Organic Lion’s Mane Mushroom Extract
Quantity Per Pack: 30 veggie caps
How To Serve It? Take one capsule every day
Guarantee: 90-day money-back guarantee
Price: $25

Lion’s mane is among the best-known and most researched medicinal mushrooms currently available. MyPure Lion’s Mane from Pure Essence delivers a significant dose of the mushroom in each pill. According to the manufacturer, this supplement supports a healthy brain function and immune response. Users should take one capsule daily to help memory, cognizance, mood, healthy brain function, and nerve growth, among other benefits.

Additionally, Pure Essence MyPure Lion’s Mane delivers another advantage over its competitors: it’s made from 100% certified organic lion’s mane mushroom extract. Users can get between 20 and 40% of beta-glucans obtained from 100% genuine mushroom fruiting compounds from each capsule.

This implies that users can get the entire organic mushroom without any artificial compounds in the finished product. Pure Essence MyPure Lion’s Mane contains only lion’s mane mushroom for maximum benefits. Besides, at an affordable price per bottle, it’s one of the best-value mushroom supplements on this list.

The Genius Brand Genius Mushrooms

Supplement Classification
Active Components: Each serving of Genius Mushrooms delivers cordyceps for performance, lion’s mane for cognition, and reishi mushroom extract for longevity. Overall, each vegetable pill is packed with proven organic mushrooms
Quantity Per Pack: 90 pills
How To Serve It? Take three pills of Genius Mushrooms daily for the best results
Guarantee: 90-day money-back guarantee
Price: $22 per bottle

Genius Mushrooms from the Genius Brand are made from lion’s mane, cordyceps, and reishi mushrooms. According to the manufacturer, it supports stress relief, energy, memory, and liver health, among other benefits. Currently, this mushroom supplement is among the best-known and most popular mushroom formulas on the internet today.

Genius Mushrooms boasts more than 22,800 reviews on Amazon, with an average rating of 4.5 stars out of 5. This makes it a popular option for those who want to enjoy the benefits of medicinal mushrooms in a nutritional supplement form.

Mushroom Revival

Supplement Classification
Active Components: Lion’s Mane mushroom, Reishi mushroom extract, Cordyceps mushroom, and other proven mushroom extracts
Quantity Per Pack: Each tincture contains 59ML mushroom extract
How To Serve It? Take two drops on your tongue with a bulb dropper
Guarantee: 90-day money-back guarantee
Price: Mushroom Revival products are currently priced at $35

Mushroom Revival is the only company on this list to accept that it’s “obsessed with the power of mushrooms.” They encourage consumers to buy their supplements to enjoy the same power too. The Mushroom Revival company runs a lineup of mushroom supplement products, including Reishi Calm Tincture, Mushroom Mix Daily 10 Tincture, Lion’s Mane Focus Tincture, and the Cordyceps Energy Tincture.

Mushroom Revival is ideal for those who want a particular mushroom blend or a mix of several mushroom extracts to help them enjoy its benefits in tincture form.

Earth Nutri Performance Energy + Focus

Supplement Classification
Active Components: Key ingredients used in this formula include cordyceps, reishi, Shiitake, king trumpet, lion’s mane, and turkey tail mushroom extracts
Quantity Per Pack: 24 sticks
How To Serve It? Take one stick every day
Guarantee: 30-day money-back guarantee
Price: The product is currently priced at $40

This company aims to improve users’ physical and mental energy by blending mushrooms and other ingredients. The Earth Nutri Performance Energy + Focus uses alpha-GPC, citicoline, organic mushroom powder, and theacrine. This formula functions as a nootropic and mushroom formula bound into one.

The Nutri performance energy focus uses a mix of several mushrooms to enhance the user’s peak power and reduce exhaustion. Besides, it claims to sustain higher activity levels for more extended periods.

These ingredients deliver up to 2000mg of mushroom extract per serving (one stick). For easy consumption, users should just mix one formula stick with water and then drink daily. Nutri performance energy focus delivers a perfect dose of high-powered mushroom energy.


Supplement Classification
Active Components: This company makes multiple types of mushroom supplements, mushroom coffees, turkey tail capsules, and mushroom powders
Quantity Per Pack: 120 capsules
How To Serve It? Take two capsules per serving with or without a meal
Guarantee: 100% happiness guarantee
Price: Starting from $35 per pack

FreshCap is among the best mushroom supplement providers to consider in 2021. By taking their supplements daily, users can get morning energy and relaxation during the night, among other targeted benefits.

According to the manufacturer, mushroom supplements from FreshCap can support immunity, energy, stamina, mental focus, and clarity, among other benefits. Users can buy a particular mushroom supplement such as the Lion’s Mane Capsules and Turkey Tail Capsules at only $35 per package. Alternatively, they can purchase synergistic blends with several mushroom extracts, such as THRIVE, which contains up to six mushroom extracts. Other combinations include Unwind, Focus, and Mushroom Coffee, among others.

FreshCap is ideal for those who want mushroom supplements with attractive and trendy packaging while delivering mushroom benefits in an easy-to-take manner. Users can also mix and match several mushroom supplements for added benefits. This even makes it easy to try several types of mushroom products at once.


Supplement Classification
Active Components: lion’s mane mushroom, Reishi mushroom, cordyceps mushroom, and Chaga mushroom extracts
Quantity Per Pack: 60 capsules
How To Serve It? Take two capsules every day for desired health results
Guarantee: 30-day money-back guarantee
Price: Currently selling for $24 per bottle

VidaCap is one of the mushroom supplement providers to consider in 2021. The company makes a range of supplements that target specific goals like Sleep. They also focus on particular mushrooms such as Reishi and Lion’s Mane supplements. VidaCap’s supplements allow users to enjoy the effects of mushroom formulas cost-effectively without compromising quality.

Each VidaCap capsule offers premium-grade mushrooms sourced from closed greenhouses in China and Russia. After harvesting, the mushrooms go through a series of processes like sun drying, screening, and milling before they’re turned into a dietary supplement.

Notably, the company ensures that every product goes through testing by a third party to confirm it’s free of heavy metals and other harmful components. While this is common with all other mushroom supplement companies, VidaCap is one of the best-value mushroom brands, especially for those looking for different benefits and a particular organic mushroom powder blend.


Supplement Classification
Active Components: This contains medicinal mushroom extracts of lion’s mane, reishi, and cordyceps mushrooms
Quantity Per Pack: A package of Shroomy gummies contains 30 mushroom-rich gummies
How To Serve It? Take one gummy daily and enjoy both taste and health
Guarantee: N/A
Price: A pack of the gummies costs $30 ($1 per day)

Shroomy is one of the only two mushroom supplements on this list available as a gummy. Shroomy gummies are advertised as nootropic mushroom blends that support cognition in multiple ways.

According to the manufacturer, the lion’s mane mushroom in each gummy serves as a proven cognition booster, which gives users greater mental clarity at work or during studies. Meanwhile, Reishi mushroom in each supplement boosts the immune system, as cordyceps support energy levels by keeping ATP production optimal.

Ceremony Mushrooms

Supplement Classification
Active Components: The products are made out of plant-based proven mushroom extracts, mushroom blends, and adaptogens
Quantity Per Pack: 118 ml
How To Serve It? Serve 2 ml every day
Guarantee: 30-day money-back guarantee
Price: A bottle of Mushroom Blend tincture from Ceremony Mushrooms costs around $45

Ceremony Mushrooms is celebrated for its mushroom tinctures. The company provides multiple mushroom-based wellness blends with targeted benefits. For instance, it makes the Stress Relief Tincture, Sleep Tincture, Mushroom Blend Tincture, and Digestion Tincture. Each tincture delivers a powerful combination of mushrooms, adaptogens, and herbs, among other plant-based ingredients.

Like other mushroom tinctures, the company prices its tinctures higher than capsules, powders, and other mushroom supplements.

Gundry MD Mushroom Vitality

Supplement Classification
Active Components: Each serving of Mushroom Vitality delivers a reishi mushroom fruiting body, Coriolus mushroom fruiting body with mycelia, and Chaga mushroom mycelia
Quantity Per Pack: 118 ML
How To Serve It? Users only need to squeeze 4ml of the tincture (about five drops) into a glass of water and then drink it daily to get the targeted benefits
Guarantee: 90-day money-back guarantee
Price: $66 per bottle

Gundry MD is a California-based company, which launched the mushroom supplement known as Mushroom Vitality. The supplement enjoys top ratings and a high price tag. However, it claims to support healthy immune function while giving users more energy in the morning.

Importantly, Mushroom Vitality is among the few mushroom supplements listed here, available as a liquid tincture. Developed by Dr. Gundry, a physician, mushroom vitality remains one of the legitimate brands over its competitors on this list. It’s also among the more expensive products.

Circadian Wellness

Supplement Classification
Active Components: Lion’s mane mushroom
Quantity Per Pack: NA
How To Serve It? NA
Guarantee: NA
Price: A bottle of Circadian Wellness mushroom formula costs $30

Circadian Wellness is known for its “Quicksome” technology, making high-quality mushroom-based supplements with specific benefits. Today, users can purchase Circadian Wellness mushroom formulas that target sleep, pain, energy, libido, and cognition, among others.

Circadian Wellness operates on the assumption that re-aligning one’s circadian rhythm is vital for a healthy mind, body, and soul. According to the manufacturer, users should take the correct dose of the supplement daily to help them restore their circadian rhythm and support optimal health.

Additionally, based on the Circadian Wellness’ Quicksome technology, users can enjoy higher absorption with lower doses of mushrooms. This mushroom formula is ideal for those looking for specific mushrooms such as lion’s mane or a combination of multiple types of mushroom extract.

VitaPost Immune Support

Supplement Classification
Active Components: Vitamin E, Green Tea extract, Beta-Glucans & Graviola Leaf, and medicinal Mushroom & Herbal mushroom Complex
Quantity Per Pack: 60 capsules
How To Serve It? Take two capsules with or without a meal
Guarantee: N/A
Price: $14 per bottle

The Immune Support mushroom supplement from VitaPost delivers a mix of plant-based and mushroom extracts to support the immune system in multiple ways. According to the manufacturer, users should take the supplement daily to supply their bodies with beta-glucans and arabinogalactan derived from advanced herbal extracts.

It also delivers antioxidants and other ingredients to support immunity in unique ways. For hundreds of years, mushroom extracts like Shiitake, maitake, and reishi have kept better immune system health. The Immune Support formula from VitaPost can give users the mushroom extracts their bodies need to support the immune system in several ways.

Immune Support is among the fairly-priced mushroom supplements on this list.

MycoPhyto Complex

Supplement Classification
Active Components: This formula delivers 1.28g of reishi, cordyceps, turkey tail, Polyporus, royal Agaricus, and maitake mushroom extracts
Quantity Per Pack: 60 vegetable capsules
How To Serve It? As stated by the manufacturer, users can take two capsules of the MycoPhyto supplement
Guarantee: 90-day money-back guarantee
Price: $39.95

This mushroom supplement combines six proven mushroom extracts into one suitable mushroom supplement.

The company has also included a dose of 50mg of beta-glucan to optimize its health-supporting benefits. Made by Advanced Bionutritionals, MycoPhyto Complex is currently available at an affordable price. However, the manufacturer offers discounts for multiple orders.

The formula is a brainchild of a medical doctor, Dr. Isaac Eliaz, MD. All the medicinal mushrooms used in this formula are scientifically-backed to prove they can support health differently.

Brain Forza Organic Lion’s Mane Mushroom

Supplement Classification
Active Components: The formula is up to six times stronger than the regular lion’s mane mushroom extracts because it delivers more than 1g of polysaccharides in each serving
Quantity Per Pack: 90 capsules
How To Serve It? Serve three capsules every day
Guarantee: 90 days money-back guarantee
Price: Starting from $40 per bottle

The Lion’s Mane Mushroom supplement from Brain Forza Organic is among the popular mushroom supplements to consider in 2021. The supplement uses USDA Organic certified, lab-grown lion’s mane mushrooms, stronger than wild-grown mushrooms. According to the manufacturer, the mushrooms are cooked twice to 125 degrees Celsius.

Brain Forza Organic advertises this supplement to help users restore brain health, neuroprotection, memory, and healthy moods, among other benefits.

Importantly, Brain Forza claims this supplement is the purest and most potent hericium currently available in the market. Besides, the formula is verified to be free of heavy metals, herbicides, pesticides, and other contaminants.

Goldmine Supershroom Powder

Supplement Classification
Active Components: The main ingredients used in this formula include ginger, lucuma, astragalus, reishi fruiting body mushroom, maitake fruiting body mushroom, and turkey tail fruiting body mushroom
Quantity Per Pack: 39 servings
How To Serve It? Users should take between 0.5 and 1 teaspoon of the formula up to three times a day to deliver tasty plant magic while supporting health benefits
Guarantee: N/A
Price: The Goldmine Supershroom Powder is currently priced at $28 per jar

Goldmine Supershroom Powder is among the most recognized names in the mushroom supplement industry today. According to the manufacturer, the formula supports better health by protecting and strengthening the immune system using antioxidant-heavy, anti-inflammatory mushrooms, and herbal extracts.

It’s one of the reasonably priced mushroom supplements on this list. Magic Mushroom

Supplement Classification
Active Components: Each formula serving contains six organic superfood ingredients such as reishi, cacao, lucuma, Chaga, ashwagandha, and cinnamon, all of which are USDA Organic certified
Quantity Per Pack: 30 servings for one month supply
How To Serve It? Take 5g per serving
Guarantee: 30-day money-back guarantee
Price: This mushroom formula is currently priced at $35

This marketplace sells the Magic Mushroom powder. While it doesn’t technically contain magic, it delivers a blend of mushroom powders with magical effects.

Importantly, tests all its products in a third-party lab to confirm their efficacy and quality. According to the company, users should use Magic Mushroom powder in drinks, recipes, oatmeal, and shakes, among other foods and beverages of choice. This mushroom formula is like a hot chocolate powder mixed with certified mushroom extracts.


Supplement Classification
Active Components: Each serving of Spore delivers cordyceps, ashwagandha, lion’s mane, Ginkgo Biloba, and other plant-based ingredients
Quantity Per Pack: 90 capsules
How To Serve It? Take three capsules every day for the best results
Guarantee: The company offers a 30-day money back guarantee on each order of this supplement
Price: $50 per pack

Spore supports daily cognitive function and eliminates brain fog for improved clarity. Besides, it improves mental energy and focus while supporting creativity, among other benefits.

Spore contains a mix of proven mushrooms with popular adaptogens that support health in multiple ways, like other mushroom supplements on this list.

Spore equally works as a natural energy booster, libido booster, anti-aging formula, and a neuroprotective supplement while offering daily cognitive support.

Vital Plan Adaptogen Recovery

Supplement Classification
Active Components: The formula contains Cordyceps, Chinese skullcap, reishi, and Rehmannia mushroom extracts to accomplish the targeted benefits
Quantity Per Pack: It comes with 60 servings per bottle, which amounts to 180 capsules
How To Serve It? Take three capsules two times a day
Guarantee: Supported by a 90-day money back guarantee
Price: Priced at $72, it’s among the steep-priced products on this list

The Adaptogen Recovery from Vital Plan is an immune support product. Developed by Dr. Bill Rawls, this adaptogenic herbal supplement strengthens immune health and makes the body more resilient.

The four mushroom extracts claim to have potent immune system effects by functioning as adaptogens. They may help the body respond effectively to physical and mental stress. Vital Plan’s Adaptogen Recovery is among the top-rated mushroom supplements available today.

The formula is ideal for those looking for immune-boosting benefits of mushrooms. Its price per serving is just similar to other medicinal mushroom products on this list.

The Drug Store Adaptogenic Mushrooms

Supplement Classification
Active Components: Cordyceps, Chaga, and reishi mushrooms
Quantity Per Pack: Contains 30 day serving
How To Serve It? Take ½ Tsp per serving
Guarantee: N/A
Price: The prices are competitive, starting from $20

This marketplace offers more than a dozen adaptogenic and medicinal mushrooms that target various health and wellness goals. Popular medicinal formulas available on this platform include Wunder Workshop, Anatome, and Glow Bar. Some formulas specifically target immunity, while others target cognition and overall health and wellness.

Based in London, UK, TheDrug.Store is a supplement company that offers a broad range of supplements. Popular products on the platform include CBD oils, nootropics, mushroom blends, and anything in between. It’s ideal for anyone looking for mushroom tinctures and medicinal mushroom tinctures, among other mushroom supplements.

Botany Cordyceps Militaris Extract

Supplement Classification
Active Components: The formula delivers 30g of cordyceps mushroom extract per package and 15 of cordycepin concentration to conveniently give users all the benefits of cordyceps
Quantity Per Pack: 30 grams
How To Serve It? Serve 500 mg daily
Guarantee: 30-day money-back guarantee
Price: Currently priced at $24 per PET single-jar

The Cordyceps Militaris Extract from Botany is one of the medicinal mushroom supplements to consider in 2021.

Each package is UV-resistant to lower the chances of degradation. The company collaborates with a third-party lab to confirm the purity of all supplements before releasing them to the public. Once tested, Botany publishes the results online for anyone to view. Cordyceps Militaris Extract is among the most trusted mushroom supplements on this list.

Plant People WonderDay

Supplement Classification
Active Components: According to the manufacturer, each gummy comes with ten functional mushrooms, including lion’s mane mushroom extract, Chaga, and reishi mushroom extracts
Quantity Per Pack: 60 gummies
How To Serve It? Enjoy two gummies daily
Guarantee: 100% satisfaction guarantee
Price: The gummies are currently priced at $30 per package

WonderDay is a medicinal mushroom supplement from Plant People. On this list, it’s the second mushroom gummy. Unlike other supplements available in powder, capsule, or tincture form, WonderDay delivers its benefits in gummy form.

These gummies are coated with a wild raspberry flavor that delivers a surprisingly good taste.

As stated by the manufacturer, medicinal mushroom gummies are designed to support stress response, mood, energy, and immunity, among other benefits.

5 Mushrooms Reserve Blend

Supplement Classification
Active Components: The 5 Mushrooms Reserve Blend is packed with lion’s mane, reishi, cordyceps, chaga, and turkey tail mushroom extracts
Quantity Per Pack: The 5 Mushrooms supplements are available in 30 servings, which amounts to 90 capsules per package
How To Serve It? Take three caps
Guarantee: N/A
Price: $30 per jar

By combining multiple mushroom extracts, the 5 Mushrooms Reserve Blend aims to deliver numerous benefits delivered from its ingredients. Some of the elements specifically target immunity, while others target cognition and brain health.

According to the manufacturers, these formulas are the “world’s grooviest mushroom supplement.” This means users can get up to four dietary supplements in one, delivering immune, mood, energy, and nootropic benefits.

It’s one of the best-value products on this list. One pack of this supplement delivers up to 1750mg of pure mushroom per serving, which amounts to 350mg of mushroom derived from each of the five constituents.


Supplement Classification
Active Components: MindHoney’s key ingredients include lion’s mane, reishi, cordyceps, and Chaga mushroom extracts. These four are the most popular and proven mushroom extracts available today. Besides, the formula delivers popular nootropics such as Neurofactor, Coffeeberry, DMAE, NALT, L-theanine, ashwagandha, and ginseng
Quantity Per Pack: 60 easy to swallow capsules
How To Serve It? Take two capsules daily
Guarantee: N/A
Price: MindHoney is currently priced at $32

MindHoney is a nootropic formula from Dose Nomadic Nutrition. As stated by the manufacturer, this supplement can support memory, cognition, focus, mood, and alertness. The formula delivers potent ingredients to improve energy production, focus, balance, mood, stress, and support immunity and wellness. It also enhances brain function and memory, among other benefits.

By taking two capsules daily, the ingredients of MindHoney provide a blend of nootropics with proven mushrooms to support cognition in multiple ways.

Vital Plan Brain Boost

Supplement Classification
Active Components: Developed by Dr. Rawls, the Brain Boost formula contains cat’s claw, lion’s mane, bacopa monnieri, Ginkgo Biloba, and ashwagandha as its key ingredients
Quantity Per Pack: 120 capsules
How To Serve It? Take four capsules daily
Guarantee: 90-day money-back guarantee
Price: The formula currently costs $48 per bottle

Brain Boost is Vital Plan’s second product on this list. This formula utilizes a similar blend of mushroom extracts to the Adaptogen Recovery supplement. It delivers a perfect dose of mushrooms the body requires to support cognition, memory, focus, energy, mood, and immunity, among other benefits.

While both formulas from Vital Plan use mushrooms, they use different types of mushrooms to deliver various targeted benefits. The Brain Boost formula could be the right choice for those looking to promote brain function more than they want to support immunity.

How We Ranked the Best Mushroom Supplements

All medicinal mushroom manufacturers claim to make mushroom supplements that deliver powerful benefits. However, only top-rated mushroom supplements do honor these promises. To develop this list of the best mushroom supplements 2021, we used the following metrics:

Proven Ingredients

The mushroom and fungi markets already contain thousands of products. Still, only a handful is used in medicinal mushroom formulas—this list of preferred mushroom supplements with proven ingredients associated with different benefits in scientific studies.

Clinically Effective Dosages

Few mushroom supplements have the right ingredients but get it wrong on dosages. There are supplements with too little of their active ingredients, which cannot achieve the intended benefits. Other mushroom supplement companies use proprietary labels to hide low dosages, making it difficult to see individual ingredient dosages. This list of preferred mushroom supplements with powerful, clinically verified dosages.

Clinical Trials and Tests

Most mushroom supplements don’t invest in clinical trials for their products. However, some mushroom supplement companies such as Onnit ensure they take their products for clinical trials to prove their quality and efficacy. This ranking was based on the amount of scientific research a supplement company provided.

Manufacturer Reputation and Transparency

Some mushroom supplement manufacturers are transparent with the details regarding their products, including ingredients, dosages, ingredient sources, and more. Others are just vague and mean with information. This list considered companies with a strong reputation for quality and transparency.

Production Methods

Mushroom supplements can be produced through a whole fruiting body or other methods. Some companies use the whole fruiting body method, which delivers all beneficial effects of mushrooms. Different companies use myceliated grain production methods where only the root of a mushroom is used. Some companies also use ‘full spectrum’ and ‘pure mycelium’ to deliver mushroom formulas with potent effects.

Extraction Methods

There are several ways to extract medicinal mushrooms and mushroom ingredients. Traditionally, people use the hot water method. However, some companies today use the alcohol or dual extraction method to deliver a maximum concentration of active ingredients in the finished product. Different mushrooms require different types of extraction. For example, lion’s mane mushrooms require hot water extractions while harder varieties like reishi don’t.

Medical Advisory Board

Some mushroom supplement manufacturers have a medical advisory board in place. Some even have real medical doctors for guidance. This gives them an additional layer of legitimacy over other mushroom supplement companies. This ranking preferred mushroom supplements that were tested, verified, and approved by a certified specialist.

Added Benefits

Medicinal mushrooms could have transformative potential. However, some mushroom supplement manufacturers exaggerate their advertised benefits. Some suggest that their products can prevent or cure diseases. This ranking preferred mushroom supplement manufacturers who maintained honesty and transparency in their advertised usefulness.

Money Back Guarantee

Individual results may vary from one user to another when using mushroom supplements. This list prefers mushroom formulas supported by a money back guarantee or customer satisfaction. This is important so that in case a product doesn’t work, the user may request a refund.

What Are The Best Mushrooms For Health?

Researchers have become interested in mycology because of the benefits mushrooms and mushroom supplements provide. Currently, there are over 1.5 million fungi species discovered. Several mushrooms have been found to have health benefits, but only a few are health-promoting. Here are a few medicinal mushrooms:

Reishi Mushroom

This is an excellent anti-inflammatory, anti-oxidant, and immune system booster. It also has antibacterial properties and can help with insomnia and chronic fatigue.

Maitake Mushroom

The maitake mushrooms contain polysaccharides that can be beneficial to the heart. It is also high in beta-glucans which can help fight cancer cells and stimulate immune function.

Chaga Mushroom

The Chaga mushroom has a very high level of antioxidants called lipophilic actives, which means they absorb easily into your body through the digestive tract instead of being excreted or oxidized by your liver as other antioxidants do. This helps reduce inflammation and relieve symptoms such as allergies, eczema, psoriasis, arthritis, cancer, and more!

Cordyceps Mushroom

Cordyceps mushroom benefits are not just limited to the traditional way of consuming it. The Cordyceps mushrooms are also used in modern medicine as a supplement for enhancing immune function, improving mood, and increasing cognitive performance. Furthermore, it may reduce the risk of cancer by helping to control blood sugar levels in diabetic patients.

Shiitake Mushroom

Shiitake mushrooms are considered to be one of the healthiest mushrooms in the world. They are high in protein, fiber, iron, B vitamins, and selenium. Shiitake mushrooms have also been found to lower cholesterol levels and protect against heart disease.

Lion’s mane mushroom

Lion’s mane mushroom is a variety of edible fungi that has been used in traditional Chinese medicine for centuries. It has been shown to have many health advantages, including the ability to improve memory and cognitive function, boost energy levels, and promote weight loss.

Turkey tail mushroom

Turkey tail mushrooms are a variety of mushrooms that is native to China. It has been used in traditional Chinese medicine for over 2,000 years and can be found in some other countries as well. Turkey Tail mushroom extract has fiber content that can help reduce cholesterol levels, improve digestion, and aid weight loss.

Medicinal Mushroom Side Effects

So far, medicinal mushroom supplements don’t have significant side effects when taken by healthy adults in standard dosages. However, some users may experience mild stomach upset or digestive discomfort with medicinal mushroom formulas. Others may experience nausea. All the same, these cases are mild and often don’t pose any significant health risk.

Users can expect severe side effects with magic mushrooms. These types of mushrooms contain psilocybin, which is a plant-based ingredient associated with psychoactive properties and hallucinations. Legal medicinal mushroom supplements don’t have any psychoactive effects. Legal mushroom extracts work in multiple ways to support health. They have no traces of psilocybin or other psychoactive compounds.

Most importantly, users should consult their healthcare providers before taking any mushroom supplement or any other supplement. This is important for those with underlying medical conditions or under any medical prescription.

History of Medicinal Mushroom Supplements

Medicinal mushroom supplements have become popular recently, as more people discover the benefits of fungi. However, mushrooms have existed for as long as anyone can imagine. In 1991, two different species of mushrooms were found in the pockets of a frozen man in an alpine glacier.

According to history, the man named Otzi lived around 3300 BCE. It’s said that Otzi used one of his mushrooms to start fires while the other mushroom protected him against parasites and infections. Similarly, Egyptian hieroglyphics equally mention mushrooms. For instance, ancient Egyptian leaders such as Pharaohs and other noblemen ate mushrooms for longevity and good health.

Mushroom benefits are also mentioned in Greek and Roman stories, where some of the greatest minds of the time, such as Seneca, Pliny, and Dioscorides, wrote about the benefits of medicinal mushrooms. In the same way, Chinese stories also refer to mushrooms from as early as 100 BCE.

Traditionally, Chinese medicine practitioners believed mushrooms could treat cancer, respiratory diseases, and other illnesses. Some of the best mushrooms and mushroom supplements used today trace their origin to ancient China. Currently, researchers and scientists talk about the benefits of medicinal mushrooms.

FAQs About Mushroom Supplements

What are medicinal mushrooms?

Medicinal mushrooms are fungi that have medicinal properties. They are used to treat a wide variety of health problems, including cancer, diabetes, cardiovascular disease, and various other chronic illnesses.

There are several types of medicinal mushrooms: Chaga, Reishi, Cordyceps, Maitake, and more.

What are magic mushrooms?

Magic mushrooms are known to induce altered states of consciousness. Magic Mushrooms can make people feel as if they are on a journey through different realms and places. The most common type of magic mushroom is the Psilocybe cubensis, which is often called shrooms or magic mushrooms because it is usually found in regions with a warm climate where it can grow naturally.

Do I need a prescription to use mushroom supplements?

Mushrooms are a dietary supplement, which means they are not subject to the same FDA regulations as medications. This means that supplements can be taken without consulting your doctor first, and there is no need for a prescription. However, mushrooms have many potential side effects such as allergic reactions, stomach pain, diarrhea, etc.

Best Mushroom Supplements Final Word

Mushroom supplements continue to become popular with each passing day. Currently, users can purchase mushroom supplements in capsules, gummies, tinctures, and powders. This makes it easy to get a daily dose of medicinal fungi in any form.

This list comes in handy when considering the best mushroom supplements to buy. The list contains carefully researched mushroom products to offer targeted benefits. Overall, users should buy from official websites or other authorized platforms. This is the best way to get a genuine product online and avoid being scammed.

RELATED:Best Nootropics (Review) Compare Top Nootropic Supplements

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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